Transmembrane Membrane Readers form a Novel Class of Proteins That Include Peripheral Phosphoinositide Recognition Domains and Viral Spikes

Membrane proteins are broadly classified as transmembrane (TM) or peripheral, with functions that pertain to only a single bilayer at a given time.Here, we explicate a class of proteins that contain both transmembrane and peripheral domains, which we dub transmembrane membrane readers (TMMRs).Their transmembrane and peripheral elements anchor them

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Intervertebral Disc-on-a-Chip as Advanced In Vitro Model for Mechanobiology Research and Drug Testing: A Review and Perspective

Discogenic back pain is one of the most diffused musculoskeletal pathologies Non Dimmable and a hurdle to a good quality of life for millions of people.Existing therapeutic options are exclusively directed at reducing symptoms, not at targeting the underlying, still poorly understood, degenerative processes.Common intervertebral disc (IVD) disease

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5G mobile communication convergence protocol architecture and key technologies in satellite internet of things system

This paper analyzes the network architecture of the Iridium system, Orbcomm system, Narrow Band-Internet of Things (NB-IoT) and Long Range Radio (Lo Ra) in Stickers the satellite 5G mobile communication system.A new Dynamic Routing based on Multi-factor Forwarding (MF-DR) protocol is proposed.This paper simulates the ladder-type data fusion algorit

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Hidradenite plantar.

Tender, battery-powered generators plantar nodules occurring in pediatric patients can be associated to different clinical entities, despite similar morphological features, therefore dermatopathology is the best technique for the definitive diagnosis.We describe the case for a 12-year-old patient with tender, red nodules on the left sole 3 days in

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